Nadia Dominici
 
			Vrije Universiteit Amsterdam
room D-629
GENERAL INTERESTS
My research centers on the development of motor abilities in children. My main goal is to elucidate the neuromotor aspects underlying the emergence of walking, and to implement this knowledge to identify an optimal rehabilitation strategy to promote normal walking in children with neuromotor disorders, in particular cerebral palsy.
ACHIEVEMENTS
Over the years I have built a strong expertise in locomotor control and neurorehabilitation, through several studies that I conducted in excellent research laboratories: the Laboratory of Neuromotor Physiology of the Santa Lucia Foundation in Rome, and the Experimental Neurorehabilitation Laboratory at the University of Zürich, and EPFL in Lausanne. This led to the publication of various articles in high-impact journals, including Science [2011, 2012] and Nature Medicine [2012, 2016].
In 2013, I was awarded the Ig Nobel prize in Physics “for discovering that some people would be physically capable of running across the surface of a pond — if those people and that pond were on the moon”.
I was awarded the Suzanne Klein-Vogelbach -Prize for the Research of Human Movement prize in 2013, a 5-year NWO (Netherlands Organisation for Scientific Research) Vidi grant and NWO Aspasia Grant in 2015, and a 5-year ERC Starting Grant (European Research Council) in 2016.
CURRENT RESEARCH
I am currently working on the interplay between brain and muscular activity underlying the development of locomotor patterns in children, as well as on the biomechanics of human locomotion. From October 2015 I am project leader and principal investigator of the project “FirSTeps – The emergence of walking in children”, and from February 2017 I am project leader and principal investigator of the project ”Learn2Walk. Brain meets spine: the neural origin of toddlers’ first steps”. My research group consists of BSc, MSc and PhD students, who work on studies related to the development of walking from neonates stepping until independent walking in healthy children and in children with neuromotor disorders.
RÉSUMÉ
After a master diploma in Physics, I received my PhD in Neuroscience at the University of Rome “Tor Vergata”, Italy, for work on the neurophysiology of locomotor development in children.
I held research positions at the Laboratory of Neuromotor Physiology of the Santa Lucia Foundation in Rome under the supervision of Prof. Francesco Lacquaniti, where I focused on central pattern generation networks and on the development of locomotion in children starting from neonate stepping until the first independent steps in toddlers, and at the Experimental Neurorehabilitation Laboratory at the University of Zürich, and at the Swiss Federal Institute of Technology Lausanne (EPFL), in Lausanne, under the supervision of Dr. Gregoire Courtine, where I developed neurorehabilitation techniques to restore walking in animals after spinal cord injuries.
In 2015, I became Assistant Professor at the Faculty of Behavioural and Movement Science at Vrije Universiteit of Amsterdam, where I established my own research laboratory. In 2016 I was nominated Associate Professor.
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Research…
- FirSteps – The Emergence of Walking in ChildrenThe first independent step of a child may be small, but it represents a giant leap for its development. This project addresses the emergence of coordination patterns and motor primitives or muscle synergies in typically developing children and in children with cerebral palsy.
- Learn2Walk – Brain meets spineWe analyze brain and muscular activity in typically developing children and in children with cerebral palsy. We seek to unravel the reorganization of cortical and cortico-muscular activity accompanying the development of walking with the ultimate aim to design novel rehabilitation techniques for cerebral palsy.
Network…
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Excerpts of scientific work
- Impaired motor control during post-stroke walking: A systematic review and meta-analysis of muscle synergies across different phases of recovery.Impaired motor control during post-stroke walking: A systematic review and meta-analysis of muscle synergies across different phases of recovery.Defour, A., Dominici, N., Swinnen, E., Cambier, D., Van Cleemput, G. & Van Bladel, A., 12 Sept 2025, (E-pub ahead of print) In: Gait and Posture. 19 p., 109978.Research output: Contribution to Journal › Review article › Academic › peer-review 
- Future climate projections in the global coastal oceanFuture climate projections in the global coastal oceanHolt, J., Katavouta, A., Hopkins, J., Amoudry, L. O., Appendini, C. M., Arneborg, L., Arnold, A., Artioli, Y., Aucan, J., Berx, B., Cagigal, L., Dominicis, M. D., Denamiel, C., Galli, G., Graham, J. A., Jacobs, Z., Jevrejeva, S., Kamranzad, B., Langlais, C. & Larsen, M. A. D. & 23 others, , Jul 2025, In: Progress in Oceanography. 235, p. 1-28 28 p., 103497.Research output: Contribution to Journal › Article › Academic › peer-review 
- From marker to markerless: Validating DeepLabCut for 2D sagittal plane gait analysis in adults and newly walking toddlersFrom marker to markerless: Validating DeepLabCut for 2D sagittal plane gait analysis in adults and newly walking toddlersVerhoeven, M., Zandvoort, C. S. & Dominici, N., Jun 2025, In: Journal of Biomechanics. 186, p. 1-7 7 p., 112708.Research output: Contribution to Journal › Article › Academic › peer-review 
- Exploring the cortical involvement in sensorimotor integration during early stages of independent walkingExploring the cortical involvement in sensorimotor integration during early stages of independent walkingKoster, R. A. J., Zandvoort, C. S., Kerkman, J. N., Daffertshofer, A. & Dominici, N., Jun 2025, In: Experimental Brain Research. 243, 6, p. 1-14 14 p., 153.Research output: Contribution to Journal › Article › Academic › peer-review 
- Feasibility and safety of automated multi-channel FES-assisted gait training in incomplete spinal cord injuryFeasibility and safety of automated multi-channel FES-assisted gait training in incomplete spinal cord injuryBerkelmans, S., Dominici, N., Afschrift, M., Bruijn, S. & Janssen, T. W. J., 26 May 2025, In: Journal of Rehabilitation Medicine.Research output: Contribution to Journal › Article › Academic › peer-review 
- Early Motor Development and Physical Activity: A Behavioral Genetic ApproachEarly Motor Development and Physical Activity: A Behavioral Genetic ApproachZi, Y., 8 Jan 2025, 301 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- The impact of ankle-foot orthotics on selective motor control during gait in children and adolescents with cerebral palsyThe impact of ankle-foot orthotics on selective motor control during gait in children and adolescents with cerebral palsyKeren, D., Goudriaan, M., Springer, S., Sorek, G., Dominici, N., van der Krogt, M. M., Buizer, A. I. & Schless, S. H., Oct 2024, In: Gait and Posture. 114, p. 48-54 7 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Lateralized modulation of cortical beta power during human gait is related to arm swingLateralized modulation of cortical beta power during human gait is related to arm swingBorhanazad, M., van Wijk, B. C. M., Buizer, A. I., Kerkman, J. N., Bekius, A., Dominici, N. & Daffertshofer, A., 19 Jul 2024, In: iScience. 27, 7, 110301.Research output: Contribution to Journal › Article › Academic › peer-review 
- Exploring harmonic walking development in children with unilateral cerebral palsy and typically developing toddlers: Insights from walking experienceExploring harmonic walking development in children with unilateral cerebral palsy and typically developing toddlers: Insights from walking experienceDe Bartolo, D., Borhanazad, M., Goudriaan, M., Bekius, A., Zandvoort, C. S., Buizer, A. I., Morelli, D., Assenza, C., Vermeulen, R. J., Martens, B. H. M., Iosa, M. & Dominici, N., Jun 2024, In: Human Movement Science. 95, 103218.Research output: Contribution to Journal › Article › Academic › peer-review 
- Balance training in older adults enhances feedback control after perturbationsBalance training in older adults enhances feedback control after perturbationsKoster, R. A. J., Alizadehsaravi, L., Muijres, W., Bruijn, S. M., Dominici, N. & van Dieën, J. H., 2024, In: PeerJ. 12, 11, p. 1-21 21 p., e18588.Research output: Contribution to Journal › Article › Academic › peer-review 
- The development of running in children: There is more to the story than flight phaseThe development of running in children: There is more to the story than flight phaseMidtgaard Bach, M., 9 May 2023, 179 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- Development of running is not related to time since onset of independent walking, a longitudinal case studyDevelopment of running is not related to time since onset of independent walking, a longitudinal case studyBach, M. M., Zandvoort, C. S., Cappellini, G., Ivanenko, Y., Lacquaniti, F., Daffertshofer, A. & Dominici, N., 16 Feb 2023, In: Frontiers in Human Neuroscience. 17, p. 1-12 12 p., 1101432.Research output: Contribution to Journal › Article › Academic › peer-review 
- Putting two and two together: Cortico-synergy analysis for posture and gaitPutting two and two together: Cortico-synergy analysis for posture and gaitZandvoort, C. S., 24 Nov 2022, 184 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- Predicting vertical ground reaction forces from 3D accelerometry using reservoir computers leads to accurate gait event detectionPredicting vertical ground reaction forces from 3D accelerometry using reservoir computers leads to accurate gait event detectionBach, M. M., Dominici, N. & Daffertshofer, A., 26 Oct 2022, In: Frontiers in Sports and Active Living. 4, p. 1-12 12 p., 1037438.Research output: Contribution to Journal › Article › Academic › peer-review 
- Cortical contributions to locomotor primitives in toddlers and adultsCortical contributions to locomotor primitives in toddlers and adultsZandvoort, C. S., Daffertshofer, A. & Dominici, N., 21 Oct 2022, In: iScience. 25, 10, p. 1-18 18 p., 105229.Research output: Contribution to Journal › Article › Academic › peer-review 
- Editorial: Rhythmic Patterns in Neuroscience and Human PhysiologyEditorial: Rhythmic Patterns in Neuroscience and Human PhysiologyDominici, N., Iosa, M., Vannozzi, G. & De Bartolo, D., May 2022, In: Frontiers in Human Neuroscience. 16, May, p. 1-3 3 p., 936090.Research output: Contribution to Journal › Editorial › Academic › peer-review 
- Muscle synergy structure and gait patterns in children with spastic cerebral palsyMuscle synergy structure and gait patterns in children with spastic cerebral palsyGoudriaan, M., Papageorgiou, E., Shuman, B. R., Steele, K. M., Dominici, N., Van Campenhout, A., Ortibus, E., Molenaers, G. & Desloovere, K., Apr 2022, In: Developmental Medicine and Child Neurology. 64, 4, p. 462-468 7 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Body Weight Control Is a Key Element of Motor Control for Toddlers’ WalkingBody Weight Control Is a Key Element of Motor Control for Toddlers’ WalkingKerkman, J. N., Zandvoort, C. S., Daffertshofer, A. & Dominici, N., Mar 2022, In: Frontiers in Network Physiology. 2, March, p. 1-12 12 p., 844607.Research output: Contribution to Journal › Article › Academic › peer-review 
- The Role of Walking Experience in the Emergence of Gait Harmony in Typically Developing ToddlersThe Role of Walking Experience in the Emergence of Gait Harmony in Typically Developing Toddlersde Bartolo, D., Zandvoort, C., Goudriaan, M., Kerkman, J., Iosa, M. & Dominici, N., Feb 2022, In: Brain Sci. 12, 2, p. 1-14 14 p., 155.Research output: Contribution to Journal › Article › Academic › peer-review 
- How wide should you view to fight? Establishing the size of the visual field necessary for grip fighting in judoHow wide should you view to fight? Establishing the size of the visual field necessary for grip fighting in judoKrabben, K., Mann, D., Lojanica, M., Mueller, D., Dominici, N., van der Kamp, J. & Savelsbergh, G., Jan 2022, In: Journal of Sports Sciences. 40, 2, p. 236-247Research output: Contribution to Journal › Article › Academic › peer-review 
- A small step towards understanding impaired walking development in children with cerebral palsyA small step towards understanding impaired walking development in children with cerebral palsyBekius, A., 24 Nov 2021, s.l.: s.n.. 175 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- What you see is not what you get: The impact of vision impairment on judo performanceWhat you see is not what you get: The impact of vision impairment on judo performanceKrabben, K. J., 4 Nov 2021, Ridderprint. 257 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- Differential sets of cortical muscle synergy signatures during adult locomotionDifferential sets of cortical muscle synergy signatures during adult locomotionZandvoort, C. S., Daffertshofer, A. & Dominici, N., 2 Jun 2021, 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER): [Proceedings]. IEEE Computer Society, p. 1070-1073 4 p. 9441206. (International IEEE/EMBS Conference on Neural Engineering, NER; vol. 2021, no. May).Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review 
- Muscle Synergies in Children Walking and Running on a TreadmillMuscle Synergies in Children Walking and Running on a TreadmillBach, M. M., Daffertshofer, A. & Dominici, N., 10 May 2021, In: Frontiers in Human Neuroscience. 15, May, p. 1-14 14 p., 637157.Research output: Contribution to Journal › Article › Academic › peer-review 
- Neuromuscular Control before and after Independent Walking Onset in Children with Cerebral PalsyNeuromuscular Control before and after Independent Walking Onset in Children with Cerebral PalsyBekius, A., Zandvoort, C. S., Kerkman, J. N., van de Pol, L. A., Vermeulen, R. J., Harlaar, J., Daffertshofer, A., Buizer, A. I. & Dominici, N., 12 Apr 2021, In: Sensors (Basel, Switzerland). 21, 8, 2714.Research output: Contribution to Journal › Article › Academic › peer-review 
- The development of mature gait patterns in children during walking and runningThe development of mature gait patterns in children during walking and runningBach, M. M., Daffertshofer, A. & Dominici, N., Apr 2021, In: European Journal of Applied Physiology. 121, 4, p. 1073-1085Research output: Contribution to Journal › Article › Academic › peer-review 
- Early Development of Locomotor Patterns and Motor Control in Very Young Children at High Risk of Cerebral Palsy, a Longitudinal Case SeriesEarly Development of Locomotor Patterns and Motor Control in Very Young Children at High Risk of Cerebral Palsy, a Longitudinal Case SeriesBekius, A., Bach, M. M., van de Pol, L. A., Harlaar, J., Daffertshofer, A., Dominici, N. & Buizer, A. I., 2021, In: Frontiers in Human Neuroscience. 15, p. 659415 659415.Research output: Contribution to Journal › Article › Academic › peer-review 
- Muscle Synergies During Walking in Children With Cerebral Palsy: A Systematic ReviewMuscle Synergies During Walking in Children With Cerebral Palsy: A Systematic ReviewBekius, A., Bach, M. M., van der Krogt, M. M., de Vries, R., Buizer, A. I. & Dominici, N., 2 Jul 2020, In: Frontiers in Physiology. 11, 632.Research output: Contribution to Journal › Article › Academic › peer-review 
- Muscle Synergies and Coherence Networks Reflect Different Modes of Coordination During WalkingMuscle Synergies and Coherence Networks Reflect Different Modes of Coordination During WalkingKerkman, J. N., Bekius, A., Boonstra, T. W., Daffertshofer, A. & Dominici, N., Jul 2020, In: Frontiers in Physiology. 11, July, p. 1-13 13 p., 751.Research output: Contribution to Journal › Article › Academic › peer-review 
- Age-related differences in muscle synergy organization during step ascent at different heights and directionsAge-related differences in muscle synergy organization during step ascent at different heights and directionsBaggen, R. J., Dieën, J. H. V., Roie, E. V., Verschueren, S. M., Giarmatzis, G., Delecluse, C. & Dominici, N., 14 Mar 2020, In: Applied Sciences (Switzerland). 10, 6, p. 1-15 15 p., 1987.Research output: Contribution to Journal › Article › Academic › peer-review 
- Motion tracking in developmental research: Methods, considerations, and applicationsMotion tracking in developmental research: Methods, considerations, and applicationsvan Schaik, J. E. & Dominici, N., 2020, New Perspectives on Early Social-cognitive Development. Hunnius, S. & Meyer, M. (eds.). Elsevier B.V., p. 89-111 23 p. (Progress in Brain Research; vol. 254).Research output: Chapter in Book / Report / Conference proceeding › Chapter › Academic › peer-review 
- Muscles on the edge: a network approach for studying motor activityMuscles on the edge: a network approach for studying motor activityKerkman, J. N., 2020, 162 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- The human sensorimotor cortex fosters muscle synergies through cortico-synergy coherenceThe human sensorimotor cortex fosters muscle synergies through cortico-synergy coherenceZandvoort, C. S., van Dieën, J. H., Dominici, N. & Daffertshofer, A., 1 Oct 2019, In: NeuroImage. 199, p. 30-37 8 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Muscle Synergies in Response to Biofeedback-Driven Gait Adaptations in Children With Cerebral PalsyMuscle Synergies in Response to Biofeedback-Driven Gait Adaptations in Children With Cerebral PalsyBooth, A. T. C., van der Krogt, M. M., Harlaar, J., Dominici, N. & Buizer, A. I., 27 Sept 2019, In: Frontiers in Physiology. 10, SEP, 1208.Research output: Contribution to Journal › Article › Academic › peer-review 
- Modular control in children with cerebral palsy during the development of walkingModular control in children with cerebral palsy during the development of walkingBekius, A., Zandvoort, C., Kerkman, J., Daffertshofer, A., Buizer, A. I., Harlaar, J. & Dominici, N., 12 May 2019.Research output: Contribution to Conference › Abstract › Academic 
- Designing Functional Training Programs to Improve Muscle Characteristics in Older Adults Using ElectromyographyDesigning Functional Training Programs to Improve Muscle Characteristics in Older Adults Using ElectromyographyBaggen, R. J., 2019, 167 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- Biofeedback to improve gait in children with cerebral palsyBiofeedback to improve gait in children with cerebral palsyBooth, A. T. C., 2019, 169 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal 
- Muscle synergies during walking in very young children with cerebral palsyMuscle synergies during walking in very young children with cerebral palsyBekius, A., Kerkman, J. N., Zandvoort, C. S., Daffertshofer, A., Harlaar, J., Buizer, A. I. & Dominici, N., May 2018, In: Developmental Medicine & Child Neurology. 60, S2, 1 p., 17.Research output: Contribution to Journal › Meeting Abstract › Academic 
- The effect of EMG processing choices on muscle synergies before and after BoNT-A treatment in cerebral palsyThe effect of EMG processing choices on muscle synergies before and after BoNT-A treatment in cerebral palsyvan der Krogt, M. M., Oudenhoven, L., Buizer, A. I., Dallmeijer, A., Dominici, N. & Harlaar, J., 2016, p. 31. 1 p.Research output: Contribution to Conference › Poster › Other research output 
- Restoring voluntary control of locomotion after paralyzing spinal cord injuryRestoring voluntary control of locomotion after paralyzing spinal cord injuryvan den Brand, R., Heutschi, J., Barraud, Q., DiGiovanna, J., Bartholdi, K., Huerlimann, M., Friedli, L., Vollenweider, I., Moraud, E. M., Duis, S., Dominici, N., Micera, S., Musienko, P. & Courtine, G., 1 Jun 2012, In: Science. 336, 6085, p. 1182-5 4 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Changes in the limb kinematics and walking-distance estimation after shank elongation: evidence for a locomotor body schema?Changes in the limb kinematics and walking-distance estimation after shank elongation: evidence for a locomotor body schema?Dominici, N., Daprati, E., Nico, D., Cappellini, G., Ivanenko, Y. P. & Lacquaniti, F., Mar 2009, In: Journal of Neurophysiology. 101, 3, p. 1419-29 11 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Changes in the limb kinematics and walking-distance estimation after shank elongation: Evidence for a locomotor body schema? (Journal of Neurophysiology (2009) 101, (1419-1429) DOI: 10.1152/jn.91165.2008)Changes in the limb kinematics and walking-distance estimation after shank elongation: Evidence for a locomotor body schema? (Journal of Neurophysiology (2009) 101, (1419-1429) DOI: 10.1152/jn.91165.2008)Dominici, N., Daprati, E., Nico, D., Cappellini, G., Ivanenko, Y. P. & Lacquaniti, F., 2009, In: Journal of Neurophysiology.Research output: Contribution to Journal › Article › Academic › peer-review 
- Development of independent walking in toddlersDevelopment of independent walking in toddlersIvanenko, Y. P., Dominici, N. & Lacquaniti, F., Apr 2007, In: Exercise and Sport Science Reviews. 35, 2, p. 67-73 7 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Control of foot trajectory in walking toddlers: adaptation to load changesControl of foot trajectory in walking toddlers: adaptation to load changesDominici, N., Ivanenko, Y. P. & Lacquaniti, F., Apr 2007, In: Journal of Neurophysiology. 97, 4, p. 2790-801 12 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Modular control of limb movements during human locomotionModular control of limb movements during human locomotionIvanenko, Y. P., Cappellini, G., Dominici, N., Poppele, R. E. & Lacquaniti, F., 2007, In: The Journal of Neuroscience. 27, 41, p. 11149-61 13 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Coordination of locomotion with voluntary movements in humansCoordination of locomotion with voluntary movements in humansIvanenko, Y. P., Cappellini, G., Dominici, N., Poppele, R. E. & Lacquaniti, F., 3 Aug 2005, In: The Journal of Neuroscience. 25, 31, p. 7238-53 16 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Kinematics in newly walking toddlers does not depend upon postural stabilityKinematics in newly walking toddlers does not depend upon postural stabilityIvanenko, Y. P., Dominici, N., Cappellini, G. & Lacquaniti, F., Jul 2005, In: Journal of Neurophysiology. 94, 1, p. 754-63 10 p.Research output: Contribution to Journal › Article › Academic › peer-review 
- Gait kinematics in newly walking toddlersGait kinematics in newly walking toddlersDominici, N., Cappellini, G., Ivanenko, Y. P. & Lacquaniti, F., Jun 2005, In: Gait & posture.Research output: Contribution to Journal › Article › Academic 
- Interaction of locomotor patterns with voluntarymovementInteraction of locomotor patterns with voluntarymovementCappellini, G., Ivanenko, Y. P., Dominici, N., Poppele, R. E. & Lacquaniti, F., Jun 2005, In: Gait & posture.Research output: Contribution to Journal › Article › Academic 
- Development of pendulum mechanism and kinematic coordination from the first unsupported steps in toddlersDevelopment of pendulum mechanism and kinematic coordination from the first unsupported steps in toddlersIvanenko, Y. P., Dominici, N., Cappellini, G., Dan, B., Cheron, G. & Lacquaniti, F., 2004, In: Journal of Experimental Biology. 207, Pt 21, p. 3797-810 14 p.Research output: Contribution to Journal › Article › Academic › peer-review 





