Interactions between disc degeneration and multifidus atrophy

The aim of this project is to understand how the mechanical effects of atrophy of the multifidus muscles, as observed in patients with low-back pain, interact with those of intervertebral disc degeneration. Disc degeneration reduces spine stiffness and may impair control over spine movement. Multifidus atrophy is assumed to result from nociceptive afference from spinal structures and may all negatively affect control over the spine. In turn, reduced control over spine movement may enhance disc degeneration.

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