As one of the leading institutes in the field of Human Movement Sciences, we conduct highly ambitious and innovative research projects. Our PhD students receive scientific and technical training from senior researchers, and are expected to become world leading scientists in their field. We see intensive guidance, and participation in a highly motivated multidisciplinary team as a key element to their success.
Florian has obtained an NWO grant for teachers to study variability of trunk movement in patients with low-back pain. He investigates whether a subgroup of patients who show stereotypical trunk movements can be identified and whether increasing movement variabilty in this subgourp affects clinical outcomes.
Leila seeks to improve diagnostics and interventions for balance problems. She assesses biomechanical, psychological and neural determinants of 'good' balance as a function of age.
Jeanine's research focus is on healthy ageing and the importance of physical activity. Part of her research is on PreventIT, a lifestyle intervention programme to prevent functional decline in young older adults.
As part of the EU funded Spexor project, Saskia studies the usability of newly developed exoskeletons to support the trunk. She aims to understand how the interaction with these devices can be optimized to prevent unwanted side-effects such as increased metabolic costs and discomfort.
The aetiology of pelvic girdle pain during pregnancy remains largely unclear. Esther investigates the development of these symptoms from a biomedical and psychosocial perspective. Her research combines qualitative studies in patients and health care professionals, with a quantitative study amongst pregnant women.
Although only in very rare occasions, manual therapy management of patients with neck pain and headache may be associated with serious adverse events. The IFOMPT framework is developed to prevent or minimise this. Rogier investigates the inter-tester reliability and validity of the IFOMPT framework among manual therapists.
Psychosocial factors influence the prognosis of patients with spinal pain. Lisette develops an e-health intervention targeting these psychosocial factors via pain education and behavioural activation. She conducts a multi-centre clinical trial to assess the additional value of this e-health intervention when combined with physiotherapy.
Carlos investigates the mechanical properties of muscle and connective tissues in patients with haemophilic arthropathy, as well as the adaptions in the neural control of gait to the reduced range of ankle and knee joint motion.
Bas studies innovations in knee arthroplasty and their effects on functional outcomes. His focus is on the application of sophisticated sensors and algorithms to assess quality of walking in the daily practice of orthopaedic surgery.
In the TTW funded project QDISC, Mariette studies trunk stabilization in low-back pain patients. Next to contributing to method development, she studies differences in trunk mechanical propeties and trunk muscle spindle reflexes between controls and patients, the latter over the course of treatment.
Funded by an NWO grant for teachers, Mohamed studies to what extent training of muscle power in older adults can contribute to enhancing physical function. He develops methods to assess and train muscle power within clinical practice and compares the outcomes to conventional training methods.
Clavicular fractures are regularly conservatively treated, which sometimes leads to considerable clavicular shortening. Robert Jan seeks to predict the effect of shortening on function and strength and to advice how and when to treat a clavicular fracture operatively or conservatively.
Norman studies how individuals adapt their movement behaviour to shoulder pain. Part of his research project has been done in collaboration with the lab for Motor Control and Pain Research at The University of Queensland. His work is funded by the NWO with a Doctoral Grant for Teachers.
Niels studies the influence of prosthetic alignment changes on amputee's gait and bone movement within a prosthetic socket. He investigates the possible use of knee and hip moments as well as socket moments and couples to optimize prosthetic functioning.
Nick investigates the alignment of the perceived and actual physical ability in older adults, and how this affects their movement behaviour in terms of stepping, normal gait, and responses to gait perturbations
As part of the EU funded Spexor project, Axel investigates how newly developed exoskeletons affect mechanical loads on the body during manual lifting. He aims to understand how humans interact with these devices and how this affects kinematics and forces at the lumbar spine.
Virtual reality is rapidly gaining interest, also in physiotherapy. Maaike investigates how virtual reality can be utilised effectively in a primary care setting in patients with neck pain. She also studies whether virtual reality might be more beneficial for patients with fear of movement.
Ton's project is part of the Citius Altius Sanius program on injury prevention in sport. He focusses on the usability of sensory systems when returning to sport in case of upper extremity injuries in elite youth tennis players and baseball players, in close cooperation with physical therapists.
Moira studies when and how active control ensures a stable gait pattern. She assesses phase-dependent muscle variations, movement strategies and corticomuscular coherence in relation to stability measures.
Carolina's research interest is sarcopenia in the oldest old population. Her studies focus on the methods of muscle mass measurements, the pathophysiology and determinants of muscle strength, and the clinical and prognostic values of strength measurements.
Stéphanie investigates the influence of physical parameters in geriatric oncology. She studies whether low muscle mass and muscle quality increase the risk of complications after surgery and during chemotherapy treatment in older patients.
The immune system is an important player in pain. Ivo investigates various inflammatory markers in the blood and spinal cord in patients with persistent neck pain. He investigates via blood analyses and PET-CT scans whether manual therapy and physiotherapy can positively influence these immune responses.
Rina studies the role of the vestibular system in maintaining stability of gait. She uses galvanic vestibular stimulation to understand the role of vestibular input in maintaining stability while walking.
Mohammed studies the control of gait stability. He is particularly interested in the metabolic cost of maintaining gait stabalility, and in differences in control of gait stability between walking and running.
Nauzef develops adaptive head and trunk supports (exoskeletons) for patients with diseases such as Duchenne Muscle Dystrophy. He aims to understand how such devices could enhance daily function in these patients.
Arjan tries to unravel the relationship between hemodynamics during postural changes and physical performance in older adults, focusing especially on orthostatic hypotension, a blood pressure drop after standing up. His goal is to find the physical consequences of this disorder and to elucidate the underlying mechanisms in order to develop targeted interventions.
Knee disorders due to a meniscal tear can be managed with physiotherapy rather than surgery in 70% of patients. Julia investigates whether these two interventions result in different rates of serious knee osteoarthritis. She also develops a statistical prediction model to identify in advance who will benefit from physiotherapy.
Ben develops algorithms to provide feedback to runners on their runnig technique, based on data obtained with wearable sensors. The overall aim is to enhance performance and to reduce injury risk, such that running can contribute to a healthy and active lifestyle.
Arjun studies the immediate and chronic effects of stroke on skeletal muscle and on the neuromechanics of locomotion. For this purpose, a photothrombotic stroke model to mimic the effects of an ischemic stroke in the motor cortex of rats is used.
Laura investigates the relation between trunk and arm movements in patients with neuromuscular diseases such as Duchenne Muscle Dystrophy and Spinal Muscular Atrophy. She aims to understand compensatory motions, in order to facilitate development of assistive devices.
Recurrent low back pain is associated with maladaptive changes in the central nervous system. Sabrine investigates which clinical tests correlate with these changes in the brain. Furthermore, she studies which specific interventions may reverse these maladaptive changes.
Maarten studies altered movement patterns as seen in low back pain. He assesses different strategies that may cause the observed movement patterns in low back pain, among which splinting behavior.
Although manual therapy has shown to be effective, its working mechanism is still largely unclear. Roland investigates to what extent central pain modulation is altered in patients with persistent neck pain and whether manual therapy has a positive influence on these mechanisms.
Markus develops a perturbation-based fall prevention training programme to reduce fall risk in the elderly. He perturbs the walking pattern to induce motor learning by training reactive response to a balance loss following a trip or slip.
Anna investigates the association between instrumented physical activity, malnutrition and health related outcome measures in older adults.
Kira concentrates on changes in muscle parameters during hospitalization, the impact of interventions, and factors influencing physical activity (promotion) behavior of both patients and professionals.
Neuropathies are among the most important complications in people with diabetes. Eva investigates the (dys)function of small and large diameter nerve fibres, neuromechanics and morphological changes of peripheral nerves. She also investigates whether physiotherapy can reduce pain in patients with painful diabetic neuropathies.
Lucas studies gait initiation with and without stepping down or over an obstacle, to unravel differences in anticipatory postural adjustments between these conditions in healthy young and older adults and in patients with Parkinson's disease.
Marije focuses on primary care patients with cervical radiculopathy. She aims to determine important factors for diagnosis and prognosis and to investigate immune responses to physical therapy treatment.
Ali studies the control of actuated exoskeletons that aim to support workers during manual work. His goal is to understand how selection of input signals and control modes can be optimized to reduce mechanical risk factors for low back pain.
Low back pain and urinary tract symptoms often coexist in men due to changes in movement patterns, habits, lifestyle and psychological factors, such as stress and fatigue due to interrupted sleep. Tom investigates the diagnosis and multidisciplinary management of these combined disorders.
Meta has obtained an NWO grant for teachers to study how trunk motor control changes with low back pain. Her project assesses the theory that changes in trunk motor control with low-back pain are based on re-optimzation of motor control based on a re-weighting of movement related costs, as a result of experiencing pain. Specifically, the influence of (the threat of) pain and the threat of loosing control over trunk motion as potential drivers of changes in motor contro are studied.
Although the majority of patients improve following lumbar micro-discectomy, an important minority continues to have significant low back pain. Stijn investigates the impact of biomedical factors on recovery. These biomedical factors in isolation may not be adequate predictors, and psychosocial factors are also be considered.
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